Warren A Chow Selected Research

site 1 membrane-bound transcription factor peptidase

7/2012	Nelfinavir inhibits regulated intramembrane proteolysis of sterol regulatory element binding protein-1 and activating transcription factor 6 in castration-resistant prostate cancer.
4/2011	Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6.

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Warren A Chow Research Topics

Disease

14	Neoplasms (Cancer) 01/2022 - 09/2004
10	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 09/2004
5	Chondrosarcoma 02/2022 - 04/2006
4	Liposarcoma 12/2012 - 09/2006
3	Osteosarcoma (Osteogenic Sarcoma) 02/2022 - 08/2014
2	Ewing Sarcoma (Sarcoma, Ewing) 02/2022 - 02/2010
2	Leiomyosarcoma 01/2022 - 01/2017
2	Alveolar Soft Part Sarcoma 01/2022 - 01/2017
2	Extraskeletal Myxoid Chondrosarcoma 01/2022 - 07/2007
2	Synovial Sarcoma (Synovioma) 10/2019 - 08/2014
2	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2018 - 08/2010
2	Prostatic Neoplasms (Prostate Cancer) 04/2015 - 07/2012
2	Lipodystrophy 12/2012 - 09/2006
2	HIV Infections (HIV Infection) 01/2009 - 09/2006
1	Melanoma (Melanoma, Malignant) 01/2022
1	Skin Neoplasms (Skin Cancer) 01/2022
1	Chordoma 01/2017
1	Solitary Fibrous Tumors 01/2017
1	Rhabdomyosarcoma 08/2014
1	Neoplasm Metastasis (Metastasis) 01/2014
1	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2009
1	Second Primary Neoplasms (Neoplasms, Second) 07/2007
1	Clear Cell Chondrosarcoma 07/2007
1	Cardiotoxicity 09/2004

Drug/Important Bio-Agent (IBA)

5	Nelfinavir (Viracept)FDA Link 04/2015 - 09/2006
3	Dasatinib (BMS 354825)FDA Link 01/2018 - 03/2016
3	Imatinib Mesylate (Gleevec)FDA Link 01/2018 - 02/2010
3	Peptide Hydrolases (Proteases)FDA Link 04/2015 - 04/2011
3	HIV Protease InhibitorsIBA 12/2012 - 09/2006
2	pazopanib FDA Link 01/2022 - 01/2014
2	Immune Checkpoint InhibitorsIBA 01/2022 - 10/2019
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2012
2	SterolsIBA 07/2012 - 09/2006
2	site 1 membrane-bound transcription factor peptidaseIBA 07/2012 - 04/2011
2	ElementsIBA 07/2012 - 09/2006
2	Biological ProductsIBA 08/2010 - 07/2007
1	cabozantinibIBA 01/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	Antineoplastic Agents (Antineoplastics)IBA 01/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 11/2020
1	Heme (Haem)IBA 11/2020
1	RNA (Ribonucleic Acid)IBA 11/2020
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 10/2019
1	AntigensIBA 10/2019
1	Peptides (Polypeptides)IBA 10/2019
1	HLA-A Antigens (HLA-A)IBA 10/2019
1	regorafenibIBA 01/2018
1	SulfurIBA 01/2018
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2018
1	Sunitinib (Sutent)FDA Link 01/2018
1	IronIBA 01/2018
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2018
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2018
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2017
1	Monoclonal AntibodiesIBA 08/2014
1	Insulin (Novolin)FDA Link 08/2014
1	teprotumumabIBA 08/2014
1	Activating Transcription Factor 6IBA 07/2012
1	Androgen Receptors (Androgen Receptor)IBA 07/2012
1	AndrogensIBA 07/2012
1	Sterol Regulatory Element Binding Protein 1IBA 04/2011
1	3,4-dichloroisocoumarinIBA 04/2011
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 04/2011
1	Small Interfering RNA (siRNA)IBA 04/2011
1	Tyrosine Kinase InhibitorsIBA 08/2010
1	Platelet-Derived Growth Factor alpha ReceptorIBA 02/2010
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 11/2009
1	GTI2040IBA 11/2009
1	Capecitabine (Xeloda)FDA Link 11/2009
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2009
1	Anti-HIV Agents (AIDS Drugs)IBA 01/2009
1	Orphan Nuclear ReceptorsIBA 07/2007
1	Ritonavir (Norvir)FDA Link 09/2006
1	Saquinavir (Invirase)FDA Link 09/2006
1	HIV ProteaseIBA 09/2006
1	amprenavir (Agenerase)FDA Link 09/2006
1	Indinavir (Crixivan)FDA Link 09/2006
1	purineIBA 04/2006
1	5'-methylthioadenosine phosphorylase (methylthioadenosine nucleosidase)IBA 04/2006
1	Pemetrexed (MTA)FDA Link 04/2006
1	Folic Acid (Vitamin M)FDA LinkGeneric 04/2006
1	Levofloxacin (Levaquin)FDA Link 09/2004
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 09/2004
1	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2004
1	Dexrazoxane (Zinecard)FDA LinkGeneric 09/2004

Therapy/Procedure

10	Drug Therapy (Chemotherapy) 02/2022 - 09/2004
8	Therapeutics 02/2022 - 07/2007
2	Castration 04/2015 - 07/2012
1	Fecal Microbiota Transplantation 01/2022
1	Immunotherapy 10/2019
1	Autologous Transplantation 08/2009
1	Highly Active Antiretroviral Therapy (HAART) 01/2009